Evidence of Anaphylaxy After Alteplase Infusion

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Evidence of anaphylaxy after alteplase infusion.

BACKGROUND AND PURPOSE Although alteplase, a recombinant tissue plasminogen activator (tPA), is structurally identical to endogenous tPA and therefore should not induce allergy, single cases of acute hypersensitivity reactions have been reported. Until now, specific antibodies against alteplase were not detected in blood samples obtained in these patients. CASE DESCRIPTION We report an anaphy...

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ژورنال

عنوان ژورنال: Stroke

سال: 1999

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.30.5.1142